Establishment of oxalate diet induced CKD Model

A diet high in soluble oxalate induced oxalate nephropathy. (A-B) Serum urea nitrogen (UREA) and creatinine (CREA) were measured at  days 7,14 and 21. Values are means ±SEM from 6 mice/group. **p<0.01 and ***p<0.001 vs. control group.

Histologic analysis in the oxalate diet induced oxalate nephropathy mouse model. (A) Representative pictures of H&E staining showing increased renal tubule dilatation and oxalate crystal deposition of Oxalate group. (B) Representative pictures of Masson staining showing increased renal tubule interstitial fibrosis of Oxalate group. Scale bar: 100 μm.